Interviews with young HIV and AIDS activists from Cambodia, Mexico, Sweden, South Africa, and the United States, on youth, HIV and AIDS.

Mary-Jane Matsolo from the Treatment Action Campaign (TAC) visits the Umbogintwini area outside of Durban and talks about the high prevalence of HIV and the limited access to health care and treatment in the area.

4th South African AIDS Conference in Durban. Closing session with a speech by South African Minister of Health, Barbara Hogan, about policies and strategies for human rights and HIV prevention interventions. Discovery Health award to scientist in the HIV field.

This film is about women from different parts of the world who are active in the HIV activist movement. They discuss gender inequality and the exposed situation of women and girls and explain the educational and empowering work which they are doing in their communities.