This is the story of four women living with HIV, who are active in the work against HIV/AIDS in Indonesia, Bolivia, Kenya and Sweden. They tell about their lives and their work with health education, advocacy, and support of women and children.

XVII International AIDS Conference in Mexico City. Interviews with activists from across the world, representing non-governmental organizations advocating for HIV prevention and the rights of youth.

Alec works as a manager in a harm reduction program and does street outreach work among young drug users in the streets of Moscow.

Julie and Ken from the Australian Prostitutes Collective talk about their program for HIV/AIDS prevention among female and male sex workers, among which one third are also IV drug users. APC offers social support, needle exchange and sex education.