Staffan Hildebrand returns to Australia, where he started his project of documenting the AIDS epidemic in 1988, and to Cambodia where he first arrived in 1998. He interviews some of the scientists and activists who he met back then and displays some footage from the archive.

XVIII International AIDS Conference in Vienna. Interview with Paula Akugizibwe from AIDS and Rights Alliance for Southern Africa (ARASA). She talks about stigma, what it is and how it is created.

This is the story of four women living with HIV, who are active in the work against HIV/AIDS in Indonesia, Bolivia, Kenya and Sweden. They tell about their lives and their work with health education, advocacy, and support of women and children.

XVII International AIDS Conference in Mexico City. Interviews with activists from across the world, representing non-governmental organizations advocating for HIV prevention and the rights of youth.

This is a short film about the global HIV and AIDS response lead by the young generation. Youths and representatives of community networks and health care centers in Cambodia, United States, Mexico, Botswana, Russia and India talk about HIV awareness and prevention.

This film tells the US story of the AIDS epidemic starting in the early 1980's. Scientists and activists, both pioneers and youths of today, talk about research, prevention, treatment and care. They also discuss stigma, homophobia and poverty as closely related to HIV and AIDS.

A film documenting the situation in Russia in 2002, highlighting the conflict between different approaches to the HIV problem.

Alec works as a manager in a harm reduction program and does street outreach work among young drug users in the streets of Moscow.

Dr Ingrid van Beek from the Sydney Medically Supervised Injecting Centre (MSIC), a program offering HIV testing, counseling, needle-exchange and methadone programs. She talks about the challenges and successes of the Australian AIDS response.

Julie and Ken from the Australian Prostitutes Collective talk about their program for HIV/AIDS prevention among female and male sex workers, among which one third are also IV drug users. APC offers social support, needle exchange and sex education.