XIX International AIDS Conference in Washington D.C. Hillary Clinton holds a speech about the political tasks of ending AIDS. Phil Wilson, founder of the Black AIDS Institute, speaks about the challenges of the communities to put an end to the epidemic.

Staffan Hildebrand looks back on his 25 years of documenting the HIV and AIDS epidemic for the Face of AIDS Film Archive. The film portrays a shift from pessimism towards a growing optimism in the response to HIV and AIDS.

XVIII International AIDS Conference in Vienna. Interview with Tahi Ganyang Butarbutar from Indonesia. He talks about HIV/AIDS activism and fighting stigma.

Interview with the Scottish Singer and AIDS activist Annie Lennox in Mexico City. She talks about her activism and the situation of poverty, violence, gender inequality and human rights violations connected with HIV/AIDS.

Interview with the Scottish Singer and AIDS activist Annie Lennox in Mexico City. She talks about her activism and the situation of poverty, violence, gender inequality and human rights violations connected with HIV/AIDS.

Cutaways from a demonstration against homophobia in Mexico City in connection with the International AIDS Conference. Interviews with Swedish HIV/AIDS activist Jan Nola Morfeldt among others.

This film is about women from different parts of the world who are active in the HIV activist movement. They discuss gender inequality and the exposed situation of women and girls and explain the educational and empowering work which they are doing in their communities.