This documentary focuses on stigma and the situation of people living with HIV in Sweden. The film focuses on the consequences of the ignorance and lack of information on HIV and AIDS. It is a story of three individuals living with HIV.

Lars Olof Kallings talks about the global AIDS situation and what the international community can do. He reflects on the role of men, women and young people in the fight against AIDS, and stresses the importance of activists and voluntary organizations.

The primary focus of this documentary is on the history of how the AIDS epidemic started in San Francisco, Los Angeles and New York in 1981. Many different stories are told about people affected or surrounded by HIV and AIDS in the early years of the epidemic.

Nobel Prize Laureate Luc Montagnier answers questions on the origin of HIV, the spreading of the virus, prevention, and the possibility of a vaccine.