This is the story of four women living with HIV, who are active in the work against HIV/AIDS in Indonesia, Bolivia, Kenya and Sweden. They tell about their lives and their work with health education, advocacy, and support of women and children.

American actress Sharon Stone talks about her memories of Rock Hudson and her work with amfAR. She reflects on AIDS and stigma, how to reach out to young people, and the importance of communication in order to change the sexual behaviors of young people.

Katharina Lindahl, Secretary General of RFSU, talks about the Swedish HIV prevention campaigns by RFSU and Aidsdelegationen in the early 1990's, and the importance of targeting youth of today with messages of HIV prevention.