XVII International AIDS Conference in Mexico City. Closing session with speeches by the Co-chairs Pedro Cahn and Luiz Enrique Soto-Ramírez., as well as the Mayor of Mexico City and the Co-Chairs of the next International AIDS Conference in Vienna in, 2010.

This film tells the US story of the AIDS epidemic starting in the early 1980's. Scientists and activists, both pioneers and youths of today, talk about research, prevention, treatment and care. They also discuss stigma, homophobia and poverty as closely related to HIV and AIDS.