XVII International AIDS Conference in Mexico City. Interview with Matthew Basilico who is a student at Harvard School of Public Health. He talks about the message of youth participation and activism at the conference and in civil society.

This film tells the US story of the AIDS epidemic starting in the early 1980's. Scientists and activists, both pioneers and youths of today, talk about research, prevention, treatment and care. They also discuss stigma, homophobia and poverty as closely related to HIV and AIDS.