XIX International AIDS Conference in Washington D.C. Hillary Clinton holds a speech about the political tasks of ending AIDS. Phil Wilson, founder of the Black AIDS Institute, speaks about the challenges of the communities to put an end to the epidemic.

Staffan Hildebrand looks back on his 25 years of documenting the HIV and AIDS epidemic for the Face of AIDS Film Archive. The film portrays a shift from pessimism towards a growing optimism in the response to HIV and AIDS.

This is the third part of the interview with Dr Anthony Fauci. Here he talks about the American AIDS movement in the early 80's with activists such as the writer Larry Kramer in the frontline, and the time when he invited the leading activists up to his office.

The primary focus of this documentary is on the history of how the AIDS epidemic started in San Francisco, Los Angeles and New York in 1981. Many different stories are told about people affected or surrounded by HIV and AIDS in the early years of the epidemic.