This is the story of four women living with HIV, who are active in the work against HIV/AIDS in Indonesia, Bolivia, Kenya and Sweden. They tell about their lives and their work with health education, advocacy, and support of women and children.

Daria Hazuda from MSD explains the virology of HIV and talks about the past clinical studies on ARV, in particular integrase inhibitors, which she has been involved in. She also reflects on HIV as an exceptional virus and how to influence a new generation of HIV researchers.

This documentary focuses on stigma and the situation of people living with HIV in Sweden. The film focuses on the consequences of the ignorance and lack of information on HIV and AIDS. It is a story of three individuals living with HIV.

The Swedish Writer Steve Sjöquist is interviewed about his life with HIV, the HIV situation in Sweden and the rest of the world and his views on the future of the epidemic.

Lars Olof Kallings talks about the global AIDS situation and what the international community can do. He reflects on the role of men, women and young people in the fight against AIDS, and stresses the importance of activists and voluntary organizations.