Panel session at the 4th South African AIDS Conference, discussing youth activism, child advocacy and women's rights in relation to HIV and AIDS. Among the speakers are Archbishop Desmond Tutu and Deputy President of South Africa Baleka Mbeti.

This film tells the US story of the AIDS epidemic starting in the early 1980's. Scientists and activists, both pioneers and youths of today, talk about research, prevention, treatment and care. They also discuss stigma, homophobia and poverty as closely related to HIV and AIDS.