Hector is a gay activist involved in the prevention work towards young LGBT persons in the Zona Rosa district in Mexico City. He talks about gender roles and gay rights in Mexico and about a comic book which they hand out to young men in this square.

The primary focus of this documentary is on the history of how the AIDS epidemic started in San Francisco, Los Angeles and New York in 1981. Many different stories are told about people affected or surrounded by HIV and AIDS in the early years of the epidemic.