XVII International AIDS Conference in Mexico City. Interview with three pioneers in the HIV/AIDS response - Dr Mervyn Silverman, Dr Paul Volberding, and Dr Lars Olof Kallings. They talk about the history of the AIDS movement.

XVII International AIDS Conference in Mexico City. Interview with Andrew Francis from the Jamaica Youth Advocacy Network (JYAN) on the importance of youth participation and influence in the policy making process and in the HIV/AIDS response.

This film tells the US story of the AIDS epidemic starting in the early 1980's. Scientists and activists, both pioneers and youths of today, talk about research, prevention, treatment and care. They also discuss stigma, homophobia and poverty as closely related to HIV and AIDS.

In the last part of the interview with Dr Anthony Fauci he reflects on the global HIV/AIDS situation and response. He also compares AIDS to other diseases such as the Bird Flu, and discusses the specific social and socioeconomic factors of HIV/AIDS.