Closing session of the XIX International AIDS Conference with speakers such as Bill Clinton, the two co-chairs of the conference Elly Katabira and Diane Havlir, US politician Nancy Pelosi, Françoise Barré-Sinoussi, and many activists and community leaders.

This film tells the US story of the AIDS epidemic starting in the early 1980's. Scientists and activists, both pioneers and youths of today, talk about research, prevention, treatment and care. They also discuss stigma, homophobia and poverty as closely related to HIV and AIDS.

Last part of the interview with the American AIDS activist and founder of Project Inform, Martin Delaney, in 2006. Here he talks about AIDS activism and the different stages of the antiretroviral drug development from AZT to triple combination treatment.

Anthony Fauci is interviewed about the progression from HIV to AIDS. He talks about HIV long-term survivors and different aspects of non-progression to AIDS. He also reflects on the future for antiretroviral drugs and HIV vaccines.