This film tells the US story of the AIDS epidemic starting in the early 1980's. Scientists and activists, both pioneers and youths of today, talk about research, prevention, treatment and care. They also discuss stigma, homophobia and poverty as closely related to HIV and AIDS.

This documentary focuses on stigma and the situation of people living with HIV in Sweden. The film focuses on the consequences of the ignorance and lack of information on HIV and AIDS. It is a story of three individuals living with HIV.

Interview with George Louis, Professor and Director at the division of Vaccine and Research at the Initiative of Human Virology (IHV) in Baltimore. He talks about the current HIV vaccine trials and reflects on the future.

Lars Olof Kallings talks about the global AIDS situation and what the international community can do. He reflects on the role of men, women and young people in the fight against AIDS, and stresses the importance of activists and voluntary organizations.

Gary Nabel, from the Vaccine Research Center (VRC) talks about engaging the scientific community and health personnel in HIV research and about the importance of international conferences to create these kinds of collaborations.

Marc Girard who is the general director of the Mérieux Foundation, talks about Cent Gardes and the collaboration between France and the USA, mainly represented by the Pasteur Institute and NIH, and about why HIV is such a complicated virus to find a vaccine for.

Dr Robert C Gallo talks about the importance of yearly AIDS congresses. He also talks about the scientific community before and during the AIDS epidemic, and puts the disease outbreak into a sociological context.

Mary Marovich, medical scientist at The Walter Reed Army Medical Center in Washington, talks about the difficulties and possibilities of eventually finding an AIDS vaccine solution.

Luc Montagnier talks about the complex virology of HIV which makes the AIDS vaccine development so difficult. He also talks about the economic and cultural advantages of using traditional medicine as a part of the ARV therapy in developing countries.

Flossie Wong-Staal is an American Molecular Biologist who has been influencial in the HIV/AIDS research since the start of the US AIDS epidemic. She is known as the first scientist to clone HIV. In this interview she talks about the work on HIV gene therapy.

José Esparza is a scientist who has been working many years at WHO and within UNAIDS. He has been known for his work on HIV vaccines. Here he talks about vaccine trials and the future development of vaccines for developing and developed countries.

Robin Weiss, a British Molecular Biologist and Professor of Viral Oncology at University College London, talks about the scientific contribution of small countries like Sweden, interdisciplinary collaborations in HIV research and HIV vaccines.