XVII International AIDS Conference in Mexico City. Dr Daria Hazuda from MSD, who has been involved in antiretroviral drug development during the past 20 years, holds a presentation. She is also interviewed about leadership and the progress of ARV and vaccine development.

This film tells the US story of the AIDS epidemic starting in the early 1980's. Scientists and activists, both pioneers and youths of today, talk about research, prevention, treatment and care. They also discuss stigma, homophobia and poverty as closely related to HIV and AIDS.

Luc Montagnier talks about the complex virology of HIV which makes the AIDS vaccine development so difficult. He also talks about the economic and cultural advantages of using traditional medicine as a part of the ARV therapy in developing countries.