The primary focus of this documentary is on the history of how the AIDS epidemic started in San Francisco, Los Angeles and New York in 1981. Many different stories are told about people affected or surrounded by HIV and AIDS in the early years of the epidemic.

MD Eric Sandström talks about the Swedish health care situation for people living with HIV and his personal experiences of working with HIV patients. He also talks about the advantages of early ARV treatment, and the organized HIV testing strategies in Sweden.