This is the story of four women living with HIV, who are active in the work against HIV/AIDS in Indonesia, Bolivia, Kenya and Sweden. They tell about their lives and their work with health education, advocacy, and support of women and children.

4th International AIDS Conference in Stockholm in 1988. Australian Judge Michael Kirby estimates the prevalence of HIV/AIDS and talks about the scientific discoveries so far. He reflects on the moral issues connected with AIDS and talks about stigma and civil rights.