Interviews with young HIV and AIDS activists from Cambodia, Mexico, Sweden, South Africa, and the United States, on youth, HIV and AIDS.

Staffan Hildebrand looks back on his 25 years of documenting the HIV and AIDS epidemic for the Face of AIDS Film Archive. The film portrays a shift from pessimism towards a growing optimism in the response to HIV and AIDS.

4th South African AIDS Conference in Durban in 2009. Interview with Broadway Actress Sheryl Lee Ralph, Founder and Ceo of the DIVA Foundation. Here she talks about human rights and the stigma towards men who have sex with men and people living with HIV/AIDS.

Opening session of the 4th South African AIDS Conference in Durban in 2009. Professor Linda Gail Bekker from University of Cape Town talks about the HIV/AIDS situation in South Africa. The film also includes music performances and location shots.

This film is about women from different parts of the world who are active in the HIV activist movement. They discuss gender inequality and the exposed situation of women and girls and explain the educational and empowering work which they are doing in their communities.

This film is about the global AIDS situation. The film starts in Europe and the United States and ends up in Zimbabwe and Uganda. It tells about the global disparities of drug access, but also about the successful HIV and AIDS responses of Thailand, Cambodia and Uganda.

Quarraisha Abdool Karim is an epidemiologist in Durban. She talks about the start of the South African AIDS epidemic and the South African AIDS response, health policies and campaigns. She explains why women are more susceptible to HIV than men are.