Staffan Hildebrand returns to Australia, where he started his project of documenting the AIDS epidemic in 1988, and to Cambodia where he first arrived in 1998. He interviews some of the scientists and activists who he met back then and displays some footage from the archive.

A film documenting the situation in Russia in 2002, highlighting the conflict between different approaches to the HIV problem.

Dr Ingrid van Beek from the Sydney Medically Supervised Injecting Centre (MSIC), a program offering HIV testing, counseling, needle-exchange and methadone programs. She talks about the challenges and successes of the Australian AIDS response.

Julie and Ken from the Australian Prostitutes Collective talk about their program for HIV/AIDS prevention among female and male sex workers, among which one third are also IV drug users. APC offers social support, needle exchange and sex education.