Opening session of the 4th South African AIDS Conference in Durban in 2009. Professor Linda Gail Bekker from University of Cape Town talks about the HIV/AIDS situation in South Africa. The film also includes music performances and location shots.

XVII International AIDS Conference in Mexico City. Interview with three pioneers in the HIV/AIDS response - Dr Mervyn Silverman, Dr Paul Volberding, and Dr Lars Olof Kallings. They talk about the history of the AIDS movement.