Julie and Ken from the Australian Prostitutes Collective talk about their program for HIV/AIDS prevention among female and male sex workers, among which one third are also IV drug users. APC offers social support, needle exchange and sex education.

Dr Robert Gallo is interviewed in the laboratory about the HIV virus and his ongoing work. He also talks with his team and discusses the question of international collaboration with Lars Olof Kallings. He answers questions about HIV and AIDS, drugs and promiscuity.

4th International AIDS Conference in Stockholm in 1988. Australian Judge Michael Kirby estimates the prevalence of HIV/AIDS and talks about the scientific discoveries so far. He reflects on the moral issues connected with AIDS and talks about stigma and civil rights.

Jonathan Mann, was a US medical doctor and influential within the World Health Organization (WHO). Here he talks about the global understanding of the disease between 1981 and 1988.

Interview with the French doctor Didier Jayle talks about his work informing students in schools about how HIV is spread and how it can be prevented. He is also asked how dealing with AIDS in his work affects his personal life.