Daria Hazuda from MSD explains the virology of HIV and talks about the past clinical studies on ARV, in particular integrase inhibitors, which she has been involved in. She also reflects on HIV as an exceptional virus and how to influence a new generation of HIV researchers.

Sten Vermund from University of Alabama reflects on the history of the global AIDS epidemic and his involvement in the field as a young scientist in the 80's. He discusses the social and economic factors of HIV/AIDS, such as stigma, poverty and the drug industry.

This film is about the global AIDS situation. The film starts in Europe and the United States and ends up in Zimbabwe and Uganda. It tells about the global disparities of drug access, but also about the successful HIV and AIDS responses of Thailand, Cambodia and Uganda.

Joep Lange discusses his views on antiretroviral drugs, both in the developing and the developed world, future improvements of HIV drugs and treatment, and a possible vaccine.

Dr George Galasso is working on HIV vaccines at NIAID. Here he talks about the scientific challenges of HIV/AIDS and the chances of developing a vaccine. He believes that one of the main focuses in HIV/AIDS research still is to find treatment for opportunistic infections.