Staffan Hildebrand returns to Australia, where he started his project of documenting the AIDS epidemic in 1988, and to Cambodia where he first arrived in 1998. He interviews some of the scientists and activists who he met back then and displays some footage from the archive.

Interview with David Cooper, Director of The Kirby Institute at the University of New South Wales.

An interview with Brendan Crabb, President of Burnet Institute, on funding, the role of philanthropy, science today and in the future.

Sharon Lewin, Australian Infectious Disease physician and researcher, talks about the advances in HIV research and challenges for the future.

Interviews with young HIV and AIDS activists from Cambodia, Mexico, Sweden, South Africa, and the United States, on youth, HIV and AIDS.

XIX International AIDS Conference. Interview with Phil Wilson, founder of the Black AIDS Institute in Los Angeles. He talks about the HIV prevalence in the US and its socioeconomic factors, about stigma and discrimination against homosexual persons.

XVII International AIDS Conference in Mexico City. Swedish Dr Lars Olof Kallings who founded the International AIDS Society (IAS) in 1988 and who is now the United Nations Special Envoy for AIDS in Eastern Europe, reflects on the history of the AIDS movement.

XVII International AIDS Conference in Mexico City. Ending of a panel session on the vaccine trials of the International AIDS Vaccine Initiative (IAVI). Seth Berkley, Alan Bernstein and Omu Anzala respond to questions from the audience.

XVII International AIDS Conference in Mexico City. Panel discussion with Annie Lennox, among others, on global health policy and how the HIV/AIDS situation affects African communities.

XVII International AIDS Conference in Mexico City. Cutaways of panel discussions with Annie Lennox and members of Oxfam International, among others, on global health policy and how the HIV/AIDS situation affects African communities.

This film tells the US story of the AIDS epidemic starting in the early 1980's. Scientists and activists, both pioneers and youths of today, talk about research, prevention, treatment and care. They also discuss stigma, homophobia and poverty as closely related to HIV and AIDS.

Young AIDS activist Ricardo Baruch talks about the international collaboration of youth activists and the AIDS situation in Mexico for LBGT persons and women in rural areas and developing countries. He also reflects on the International AIDS Conference.