Staffan Hildebrand returns to Australia, where he started his project of documenting the AIDS epidemic in 1988, and to Cambodia where he first arrived in 1998. He interviews some of the scientists and activists who he met back then and displays some footage from the archive.

Hector is a gay activist involved in the prevention work towards young LGBT persons in the Zona Rosa district in Mexico City. He talks about gender roles and gay rights in Mexico and about a comic book which they hand out to young men in this square.

Young AIDS activist Ricardo Baruch talks about the international collaboration of youth activists and the AIDS situation in Mexico for LBGT persons and women in rural areas and developing countries. He also reflects on the International AIDS Conference.

Last part of the interview with the American AIDS activist and founder of Project Inform, Martin Delaney, in 2006. Here he talks about AIDS activism and the different stages of the antiretroviral drug development from AZT to triple combination treatment.