Staffan Hildebrand returns to Australia, where he started his project of documenting the AIDS epidemic in 1988, and to Cambodia where he first arrived in 1998. He interviews some of the scientists and activists who he met back then and displays some footage from the archive.

XIX International AIDS Conference in Washington D.C. Demonstration for the rights of sex workers and people who use drugs.

XIX International AIDS Conference in Washington D.C. Music performance for the rights of sex workers, by sex workers from around the world. Due to travel restrictions some of the performers are broadcasted live from India.

XVIII International AIDS Conference in Vienna. Interview with Ruth Morgan Thomas from United Kingdom who works with sex workers rights. Ruth is the Global Coordinator of the organization Global Network of Sex Work Projects (NSWP). She talks about stigma.

XVII International AIDS Conference in Mexico City. Cutaways from a demonstration for sex workers' rights.

This is a short film about the global HIV and AIDS response lead by the young generation. Youths and representatives of community networks and health care centers in Cambodia, United States, Mexico, Botswana, Russia and India talk about HIV awareness and prevention.

Two outreach workers from Men's Health Cambodia (MHC) talk about the work targeting men who sell sex in Phnom Penh.

A film documenting the situation in Russia in 2002, highlighting the conflict between different approaches to the HIV problem.

Dr Ingrid van Beek from the Sydney Medically Supervised Injecting Centre (MSIC), a program offering HIV testing, counseling, needle-exchange and methadone programs. She talks about the challenges and successes of the Australian AIDS response.

Julie and Ken from the Australian Prostitutes Collective talk about their program for HIV/AIDS prevention among female and male sex workers, among which one third are also IV drug users. APC offers social support, needle exchange and sex education.