This is the story of four women living with HIV, who are active in the work against HIV/AIDS in Indonesia, Bolivia, Kenya and Sweden. They tell about their lives and their work with health education, advocacy, and support of women and children.

Katharina Lindahl, Secretary General of RFSU, talks about the Swedish HIV prevention campaigns by RFSU and Aidsdelegationen in the early 1990's, and the importance of targeting youth of today with messages of HIV prevention.

This is a short film about the global HIV and AIDS response lead by the young generation. Youths and representatives of community networks and health care centers in Cambodia, United States, Mexico, Botswana, Russia and India talk about HIV awareness and prevention.

Interview with Daniel Tarantola, Professor of Health and Human Rights at University of New South Wales in Sydney. He tells about his work in expanding health care services in several African countries, starting in the early 1970's and the time when he entered the HIV field.

This film is about women from different parts of the world who are active in the HIV activist movement. They discuss gender inequality and the exposed situation of women and girls and explain the educational and empowering work which they are doing in their communities.

The Swedish Writer Steve Sjöquist is interviewed about his life with HIV, the HIV situation in Sweden and the rest of the world and his views on the future of the epidemic.

Lars Olof Kallings talks about the global AIDS situation and what the international community can do. He reflects on the role of men, women and young people in the fight against AIDS, and stresses the importance of activists and voluntary organizations.