XVII International AIDS Conference in Mexico City. Jeffrey Sturchio, Vice President of Merck & Co, talks about the development of protease inhibitors in 1996 and the relationship between the activists and the drug industry.

M.D. Mervyn Silverman is one of the pioneers in the HIV/AIDS epidemic. Here he talks about the shifts of topics on the International AIDS Conferences between 1985 and 2008, about the so called San Francisco Model of AIDS care, and about the closing of the Bathhouses.

This film tells the US story of the AIDS epidemic starting in the early 1980's. Scientists and activists, both pioneers and youths of today, talk about research, prevention, treatment and care. They also discuss stigma, homophobia and poverty as closely related to HIV and AIDS.

The Swedish Writer Steve Sjöquist is interviewed about his life with HIV, the HIV situation in Sweden and the rest of the world and his views on the future of the epidemic.