Staffan Hildebrand returns to Australia, where he started his project of documenting the AIDS epidemic in 1988, and to Cambodia where he first arrived in 1998. He interviews some of the scientists and activists who he met back then and displays some footage from the archive.

Martin Dishman is an American who runs the first gay bar in Siem Reap. Here he tells about himself and his bar. He also talks about the situation for lesbian women and men who have sex with men in Cambodia, and reflects on the Cambodian HIV/AIDS response.

Second and last part of the interview with UNAIDS coordinator Tony Lisle. Here he talks about the UNAIDS leadership and community-based work targeting male sex workers. He also explains why it is particularly difficult to reach out to male sex workers.

First part of the interview with Tony Lisle, UNAIDS country coordinator in Cambodia. He talks about the difficult situation for men who have sex with men and male sex workers in Cambodia.

This film is about the global AIDS situation. The film starts in Europe and the United States and ends up in Zimbabwe and Uganda. It tells about the global disparities of drug access, but also about the successful HIV and AIDS responses of Thailand, Cambodia and Uganda.