Professor Sikhamani Rajasekaran, Supervisor of the Tambaram Hospital in Chennai, talks about the HIV/AIDS outbreak in India, the prevalence of TB co-infection and the services at Tambaram Hospital as well as the need for second-line antiretroviral treatment options.

This film is about the global AIDS situation. The film starts in Europe and the United States and ends up in Zimbabwe and Uganda. It tells about the global disparities of drug access, but also about the successful HIV and AIDS responses of Thailand, Cambodia and Uganda.

Anthony Fauci is interviewed about the progression from HIV to AIDS. He talks about HIV long-term survivors and different aspects of non-progression to AIDS. He also reflects on the future for antiretroviral drugs and HIV vaccines.