The Swedish professor Emeritus in Infectious Diseases at Karolinska Institutet is interviewed about his memories and work as infectious disease physician in the 1980’s.

Interview with Daniel Tarantola, Professor of Health and Human Rights at University of New South Wales in Sydney. He tells about his work in expanding health care services in several African countries, starting in the early 1970's and the time when he entered the HIV field.

Luc Montagnier talks about the complex virology of HIV which makes the AIDS vaccine development so difficult. He also talks about the economic and cultural advantages of using traditional medicine as a part of the ARV therapy in developing countries.

The primary focus of this documentary is on the history of how the AIDS epidemic started in San Francisco, Los Angeles and New York in 1981. Many different stories are told about people affected or surrounded by HIV and AIDS in the early years of the epidemic.