Interviews with young HIV and AIDS activists from Cambodia, Mexico, Sweden, South Africa, and the United States, on youth, HIV and AIDS.

XIX International AIDS Conference. Interview with Phil Wilson, founder of the Black AIDS Institute in Los Angeles. He talks about the HIV prevalence in the US and its socioeconomic factors, about stigma and discrimination against homosexual persons.

XVII International AIDS Conference in Mexico City. Swedish Dr Lars Olof Kallings who founded the International AIDS Society (IAS) in 1988 and who is now the United Nations Special Envoy for AIDS in Eastern Europe, reflects on the history of the AIDS movement.

XVII International AIDS Conference in Mexico City. Ending of a panel session on the vaccine trials of the International AIDS Vaccine Initiative (IAVI). Seth Berkley, Alan Bernstein and Omu Anzala respond to questions from the audience.

XVII International AIDS Conference in Mexico City. Panel discussion with Annie Lennox, among others, on global health policy and how the HIV/AIDS situation affects African communities.

XVII International AIDS Conference in Mexico City. Cutaways of panel discussions with Annie Lennox and members of Oxfam International, among others, on global health policy and how the HIV/AIDS situation affects African communities.

This film tells the US story of the AIDS epidemic starting in the early 1980's. Scientists and activists, both pioneers and youths of today, talk about research, prevention, treatment and care. They also discuss stigma, homophobia and poverty as closely related to HIV and AIDS.

Young AIDS activist Ricardo Baruch talks about the international collaboration of youth activists and the AIDS situation in Mexico for LBGT persons and women in rural areas and developing countries. He also reflects on the International AIDS Conference.

In the last part of the interview with Dr Anthony Fauci he reflects on the global HIV/AIDS situation and response. He also compares AIDS to other diseases such as the Bird Flu, and discusses the specific social and socioeconomic factors of HIV/AIDS.

XVI International AIDS Conference in Toronto in August, 2006. Closing session with music performance and presentations of the Mexican representatives of the International AIDS Society. They speak about the 2008 International AIDS Conference in Mexico.

Sten Vermund from University of Alabama reflects on the history of the global AIDS epidemic and his involvement in the field as a young scientist in the 80's. He discusses the social and economic factors of HIV/AIDS, such as stigma, poverty and the drug industry.

The primary focus of this documentary is on the history of how the AIDS epidemic started in San Francisco, Los Angeles and New York in 1981. Many different stories are told about people affected or surrounded by HIV and AIDS in the early years of the epidemic.