This film is about the global AIDS situation. The film starts in Europe and the United States and ends up in Zimbabwe and Uganda. It tells about the global disparities of drug access, but also about the successful HIV and AIDS responses of Thailand, Cambodia and Uganda.

The primary focus of this documentary is on the history of how the AIDS epidemic started in San Francisco, Los Angeles and New York in 1981. Many different stories are told about people affected or surrounded by HIV and AIDS in the early years of the epidemic.

Flossie Wong-Staal is an American Molecular Biologist who has been influencial in the HIV/AIDS research since the start of the US AIDS epidemic. She is known as the first scientist to clone HIV. In this interview she talks about the work on HIV gene therapy.

MD Eric Sandström talks about the Swedish health care situation for people living with HIV and his personal experiences of working with HIV patients. He also talks about the advantages of early ARV treatment, and the organized HIV testing strategies in Sweden.

Fernando Aiuti is an Italian Immunologist who has been working on HIV/AIDS since the early 80's. In this interview he talks about the Italian AIDS situation, sexuality education and the scientific and clinical work in the field.

Interview with Agneta Dreber from Folkhälsomyndigheten (National Institute of Public Health) in Sweden. She talks about the Swedish HIV/AIDS situation, about sexuality education in schools and HIV/AIDS education in workplaces.

Robin Weiss, a British Molecular Biologist and Professor of Viral Oncology at University College London, talks about the scientific contribution of small countries like Sweden, interdisciplinary collaborations in HIV research and HIV vaccines.

Geoffrey Schild, Virologist and Director of the National Institute for Biological Standards and Control (NIBSC), talks about the Swedish contributions to AIDS research and collaboration with funding agencies such as Nutek, and reflects on HIV vaccines.

Dr George Galasso is working on HIV vaccines at NIAID. Here he talks about the scientific challenges of HIV/AIDS and the chances of developing a vaccine. He believes that one of the main focuses in HIV/AIDS research still is to find treatment for opportunistic infections.

This production from 1990 debates the worldwide HIV/AIDS situation for women and children. The stigmatization of female sexuality is considered the primary reason of women's particularly exposed situation when it comes to sexually transmitted diseases.