Two interviews with Dr Mervyn Silverman, from 1988 and 2008. He explains the San Francisco model, how it began and what others can learn from it.

XIX International AIDS Conference in Washington D.C. Interview with Ruy Burgos Filhos from Brazil. He talks about the Brazilian AIDS response and their legislation of access to ARV treatment and care for people living with HIV/AIDS in Brazil.

XIX International AIDS Conference. Interview with Gregg Alton from the Gilead Sciences, Inc. a pharmaceutical company working with health care services, policy makers, etc. to develop effective treatment, treatment as prevention and promoting access to care.

Mary-Jane Matsolo from the Treatment Action Campaign (TAC) visits the Umbogintwini area outside of Durban and talks about the high prevalence of HIV and the limited access to health care and treatment in the area.

XVII International AIDS Conference in Mexico City. Swedish Dr Lars Olof Kallings who founded the International AIDS Society (IAS) in 1988 and who is now the United Nations Special Envoy for AIDS in Eastern Europe, reflects on the history of the AIDS movement.

XVII International AIDS Conference in Mexico City. Interviews with Jasmine Burnett from the Black AIDS Institute in the United States, Yvette Fleming from Stop AIDS Now in the Netherlands and David Lush from Positive Vibes in Namibia, among others.

XVII International AIDS Conference in Mexico City. Interview with Fatma Hacioglu from Turkey and David Jason Wessenaar from South Africa, two advocates for youth sexual and reproductive rights. They talk about sexuality education in their home countries.

Joep Lange discusses his views on antiretroviral drugs, both in the developing and the developed world, future improvements of HIV drugs and treatment, and a possible vaccine.