American actress Sharon Stone talks about her memories of Rock Hudson and her work with amfAR. She reflects on AIDS and stigma, how to reach out to young people, and the importance of communication in order to change the sexual behaviors of young people.

Dr Selma Dritz tells the story of how the AIDS epidemic started in Los Angeles and San Francisco in the early 80's and how AIDS was connected to the gay liberation movement. She also talks about the government and community responses at that time.

Helene Gayle is an AIDS expert who has been working in many different initiatives in the US, among them the Centers for Disease Control (CDC). She also works in President Obama's advisory group on HIV/AIDS. Here she talks about understanding and changing behaviors.

This production was made as the opening film for the IV International AIDS Conference in Stockholm in June 1988. It gives a broad representation of the global AIDS situation in the late 1980's, and has a particular focus on social structures, poverty and stigma.

Jonathan Mann, was a US medical doctor and influential within the World Health Organization (WHO). Here he talks about the global understanding of the disease between 1981 and 1988.