Staffan Hildebrand returns to Australia, where he started his project of documenting the AIDS epidemic in 1988, and to Cambodia where he first arrived in 1998. He interviews some of the scientists and activists who he met back then and displays some footage from the archive.

XIX International AIDS Conference. Interview with Michel Kazatzhkine who is the United Nations HIV Special Representative for Eastern Europe and Central Asia. Here he talks about harm reduction policies and the situation for people who are using drugs.

XIX International AIDS Conference opening ceremony. Speeches by the Elizabeth Taylor award winners of 2012, political and religious leaders, leaders of international agencies such as UNAIDS, IAS, The Global Fund, The World Bank and UN, and many other delegates.

Closing session of the XIX International AIDS Conference with speakers such as Bill Clinton, the two co-chairs of the conference Elly Katabira and Diane Havlir, US politician Nancy Pelosi, Françoise Barré-Sinoussi, and many activists and community leaders.

XIX International AIDS Conference in Washington D.C. Memory session of the AIDS activist Robert Carr, discussing discrimination of women, MSM, sex workers and drug users as well as people living with HIV/AIDS, and tributing Robert's work and friendship.

XIX International AIDS Conference press conference with Hollywood celebrity Debra Messing.

XVIII International AIDS Conference in Vienna. Interview with Richard Marlink, Professor at Harvard School of Public Health. He talks about a symposium on the history of HIV/AIDS and future strategies for ending AIDS, that was planned in Boston in 2011.

Young AIDS activist Ricardo Baruch talks about the international collaboration of youth activists and the AIDS situation in Mexico for LBGT persons and women in rural areas and developing countries. He also reflects on the International AIDS Conference.

In the last part of the interview with Dr Anthony Fauci he reflects on the global HIV/AIDS situation and response. He also compares AIDS to other diseases such as the Bird Flu, and discusses the specific social and socioeconomic factors of HIV/AIDS.

XVI International AIDS Conference in Toronto in August, 2006. Closing session with music performance and presentations of the Mexican representatives of the International AIDS Society. They speak about the 2008 International AIDS Conference in Mexico.

Sten Vermund from University of Alabama reflects on the history of the global AIDS epidemic and his involvement in the field as a young scientist in the 80's. He discusses the social and economic factors of HIV/AIDS, such as stigma, poverty and the drug industry.

This film is about the global AIDS situation. The film starts in Europe and the United States and ends up in Zimbabwe and Uganda. It tells about the global disparities of drug access, but also about the successful HIV and AIDS responses of Thailand, Cambodia and Uganda.