Opening session of the 4th South African AIDS Conference in Durban in 2009. Professor Linda Gail Bekker from University of Cape Town talks about the HIV/AIDS situation in South Africa. The film also includes music performances and location shots.

XVII International AIDS Conference in Mexico City. Interview with three pioneers in the HIV/AIDS response - Dr Mervyn Silverman, Dr Paul Volberding, and Dr Lars Olof Kallings. They talk about the history of the AIDS movement.

Cutaways from a demonstration against homophobia in Mexico City in connection with the International AIDS Conference. Interviews with Swedish HIV/AIDS activist Jan Nola Morfeldt among others.

XVI International AIDS Conference in Toronto in August, 2006. Closing session with music performance and presentations of the Mexican representatives of the International AIDS Society. They speak about the 2008 International AIDS Conference in Mexico.