This film is about the global AIDS situation. The film starts in Europe and the United States and ends up in Zimbabwe and Uganda. It tells about the global disparities of drug access, but also about the successful HIV and AIDS responses of Thailand, Cambodia and Uganda.

Story from The Project Inform AIDS Hotline where people can call in and ask questions about HIV/AIDS and antiretroviral treatment. One of the volunteers is answering the phone.

An agent from the AIDS NGO organization KHANA educates HIV/AIDS prevention by talking to some people and handing out information sheets on the street of Phnom Penh.

Cutaways of a Kunzwana HIV/AIDS Training Project awareness session. Members of the Kunzwana Women’s Association singing and dancing. Location shots of the landscape and two motorcyclists arriving to the center.

Quarraisha Abdool Karim is an epidemiologist in Durban. She talks about the start of the South African AIDS epidemic and the South African AIDS response, health policies and campaigns. She explains why women are more susceptible to HIV than men are.

Dr Ingrid van Beek from the Sydney Medically Supervised Injecting Centre (MSIC), a program offering HIV testing, counseling, needle-exchange and methadone programs. She talks about the challenges and successes of the Australian AIDS response.

MD Eric Sandström talks about the Swedish health care situation for people living with HIV and his personal experiences of working with HIV patients. He also talks about the advantages of early ARV treatment, and the organized HIV testing strategies in Sweden.

Interview with Agneta Dreber from Folkhälsomyndigheten (National Institute of Public Health) in Sweden. She talks about the Swedish HIV/AIDS situation, about sexuality education in schools and HIV/AIDS education in workplaces.

Jamaican physician Dorothy Blake explains how other sexually transmitted diseases can make HIV easier to catch. She also talks about three main aspects of HIV prevention, which for instance includes a safe sex approach rather than a behavior modification approach.