Staffan Hildebrand looks back on his 25 years of documenting the HIV and AIDS epidemic for the Face of AIDS Film Archive. The film portrays a shift from pessimism towards a growing optimism in the response to HIV and AIDS.

This is the story of four women living with HIV, who are active in the work against HIV/AIDS in Indonesia, Bolivia, Kenya and Sweden. They tell about their lives and their work with health education, advocacy, and support of women and children.

Gracia Violeta Ross Quiroga and Juan Carlos Reja, co-founders of a Bolivian organization of people living with HIV/AIDS called REDBOL, talk about the gender roles in Bolivia and the violence against women, transgender persons and men who have sex with men.