This is the story of four women living with HIV, who are active in the work against HIV/AIDS in Indonesia, Bolivia, Kenya and Sweden. They tell about their lives and their work with health education, advocacy, and support of women and children.

American actress Sharon Stone talks about her memories of Rock Hudson and her work with amfAR. She reflects on AIDS and stigma, how to reach out to young people, and the importance of communication in order to change the sexual behaviors of young people.

XVII International AIDS Conference in Mexico City. Interview with the Canadian rapper Eternia who works with the 411 Initiative for Change. She tells about how she got involved in HIV/AIDS activism and the messages which she conveys through her music.

Interview with the Scottish Singer and AIDS activist Annie Lennox in Mexico City. She talks about her activism and the situation of poverty, violence, gender inequality and human rights violations connected with HIV/AIDS.

Interview with the Scottish Singer and AIDS activist Annie Lennox in Mexico City. She talks about her activism and the situation of poverty, violence, gender inequality and human rights violations connected with HIV/AIDS.

Mechai Viravaidya, also known as "Mr Condom", educates people in night clubs, bars and on the streets about the use of condoms to prevent HIV/AIDS.