Staffan Hildebrand returns to Australia, where he started his project of documenting the AIDS epidemic in 1988, and to Cambodia where he first arrived in 1998. He interviews some of the scientists and activists who he met back then and displays some footage from the archive.

David Penington, Australian doctor, academic, Vice-Chancellor and director, discusses strategies in the Australian HIV response.

XIX International AIDS Conference. Interview with Michel Kazatzhkine who is the United Nations HIV Special Representative for Eastern Europe and Central Asia. Here he talks about harm reduction policies and the situation for people who are using drugs.

XIX International AIDS Conference in Washington D.C. Interview with Seyed Ramin-Radfar from Tehran, Iran. He is part of IAS-NIDA Fellowship on HIV and drug use.

XIX International AIDS Conference in Washington D.C. Session on drug policy with speakers from the political and scientific community. They talk about harm reduction and political leadership. Chaired by Christopher Beyrer from John Hopkins University.

XVII International AIDS Conference in Mexico City. Interviews with activists from across the world, representing non-governmental organizations advocating for HIV prevention and the rights of youth.

A film documenting the situation in Russia in 2002, highlighting the conflict between different approaches to the HIV problem.

Alec works as a manager in a harm reduction program and does street outreach work among young drug users in the streets of Moscow.

Dr Ingrid van Beek from the Sydney Medically Supervised Injecting Centre (MSIC), a program offering HIV testing, counseling, needle-exchange and methadone programs. She talks about the challenges and successes of the Australian AIDS response.

Helene Gayle is an AIDS expert who has been working in many different initiatives in the US, among them the Centers for Disease Control (CDC). She also works in President Obama's advisory group on HIV/AIDS. Here she talks about understanding and changing behaviors.

Fernando Aiuti is an Italian Immunologist who has been working on HIV/AIDS since the early 80's. In this interview he talks about the Italian AIDS situation, sexuality education and the scientific and clinical work in the field.

Julie and Ken from the Australian Prostitutes Collective talk about their program for HIV/AIDS prevention among female and male sex workers, among which one third are also IV drug users. APC offers social support, needle exchange and sex education.