XIX International AIDS Conference in Washington D.C. Barton Haynes from the Duke Human Vaccine Institute (DHVI) has been working in the HIV vaccine field since 1985. Here he talks about the scientific difficulties of finding an HIV vaccine.

XIX International AIDS Conference. Matias Ostrowski from University of Buenos Aires is part of the CNIHR program lead by IAS and NIH. He is involved in basic research on the cell biology of HIV with the target of creating new ideas for drug development.

XIX International AIDS Conference. Session focusing on the scientific strategies in HIV cure research, ethical questions in clinical HIV cure trials and the patient benefits of those clinical trials. The panel members are scientists and physicians, activists and long-term survivors.

XIX International AIDS Conference. Lecture on SAMHD1 proteins by a scientist from the French vaccine research institute ANRS. The French Minister of Higher Education and Research holds a speech about the French-American collaboration in vaccine research.

XVII International AIDS Conference in Mexico City. Dr Daria Hazuda from MSD, who has been involved in antiretroviral drug development during the past 20 years, holds a presentation. She is also interviewed about leadership and the progress of ARV and vaccine development.

Daria Hazuda from MSD explains the virology of HIV and talks about the past clinical studies on ARV, in particular integrase inhibitors, which she has been involved in. She also reflects on HIV as an exceptional virus and how to influence a new generation of HIV researchers.

French virologist and Nobel Prize winner Luc Montagnier reflects on the discovery of HIV, discusses disappointments and lessons learned along the way and the possibility of a vaccine, and gives advice for future AIDS researchers.

Gary Nabel, from the Vaccine Research Center (VRC) talks about engaging the scientific community and health personnel in HIV research and about the importance of international conferences to create these kinds of collaborations.

Marc Girard who is the general director of the Mérieux Foundation, talks about Cent Gardes and the collaboration between France and the USA, mainly represented by the Pasteur Institute and NIH, and about why HIV is such a complicated virus to find a vaccine for.

Luc Montagnier talks about the complex virology of HIV which makes the AIDS vaccine development so difficult. He also talks about the economic and cultural advantages of using traditional medicine as a part of the ARV therapy in developing countries.

The primary focus of this documentary is on the history of how the AIDS epidemic started in San Francisco, Los Angeles and New York in 1981. Many different stories are told about people affected or surrounded by HIV and AIDS in the early years of the epidemic.

Robin Weiss, a British Molecular Biologist and Professor of Viral Oncology at University College London, talks about the scientific contribution of small countries like Sweden, interdisciplinary collaborations in HIV research and HIV vaccines.