French virologist and Nobel Prize winner Luc Montagnier reflects on the discovery of HIV, discusses disappointments and lessons learned along the way and the possibility of a vaccine, and gives advice for future AIDS researchers.

Dr Luc Montagnier and Dr Lars Olof Kallings in Montagnier’s office and laboratory at the Pasteur Institute in Paris. They talk about the HIV virus and the difficulties and possibilities of finding effective antiretroviral drug combinatoions in the future.