Staffan Hildebrand returns to Australia, where he started his project of documenting the AIDS epidemic in 1988, and to Cambodia where he first arrived in 1998. He interviews some of the scientists and activists who he met back then and displays some footage from the archive.

XVII International AIDS Conference in Mexico City. Interviews with activists from across the world, representing non-governmental organizations advocating for HIV prevention and the rights of youth.

Second and last part of the interview with UNAIDS coordinator Tony Lisle. Here he talks about the UNAIDS leadership and community-based work targeting male sex workers. He also explains why it is particularly difficult to reach out to male sex workers.

Interview with Moises who has been working with HIV prevention since 2000. Here he tells about the Mexican NGO AcciónH and the condom promotion they do in gay bars in Mexico City.

Young AIDS activist Ricardo Baruch talks about the international collaboration of youth activists and the AIDS situation in Mexico for LBGT persons and women in rural areas and developing countries. He also reflects on the International AIDS Conference.

First part of the interview with the American AIDS activist and founder of Project Inform, Martin Delaney, in 2006. He talks about the HIV/AIDS policy of the current and previous American Presidents, and reflects on his experiences of the start of AIDS in the 80's.

A film documenting the situation in Russia in 2002, highlighting the conflict between different approaches to the HIV problem.

Alec works as a manager in a harm reduction program and does street outreach work among young drug users in the streets of Moscow.