Staffan Hildebrand returns to Australia, where he started his project of documenting the AIDS epidemic in 1988, and to Cambodia where he first arrived in 1998. He interviews some of the scientists and activists who he met back then and displays some footage from the archive.

Interview with Moises who has been working with HIV prevention since 2000. Here he tells about the Mexican NGO AcciónH and the condom promotion they do in gay bars in Mexico City.

Hector is a gay activist involved in the prevention work towards young LGBT persons in the Zona Rosa district in Mexico City. He talks about gender roles and gay rights in Mexico and about a comic book which they hand out to young men in this square.

Young AIDS activist Ricardo Baruch talks about the international collaboration of youth activists and the AIDS situation in Mexico for LBGT persons and women in rural areas and developing countries. He also reflects on the International AIDS Conference.

First part of the interview with the American AIDS activist and founder of Project Inform, Martin Delaney, in 2006. He talks about the HIV/AIDS policy of the current and previous American Presidents, and reflects on his experiences of the start of AIDS in the 80's.

A film documenting the situation in Russia in 2002, highlighting the conflict between different approaches to the HIV problem.

This film is about the global AIDS situation. The film starts in Europe and the United States and ends up in Zimbabwe and Uganda. It tells about the global disparities of drug access, but also about the successful HIV and AIDS responses of Thailand, Cambodia and Uganda.

Dr Ingrid van Beek from the Sydney Medically Supervised Injecting Centre (MSIC), a program offering HIV testing, counseling, needle-exchange and methadone programs. She talks about the challenges and successes of the Australian AIDS response.