Staffan Hildebrand returns to Australia, where he started his project of documenting the AIDS epidemic in 1988, and to Cambodia where he first arrived in 1998. He interviews some of the scientists and activists who he met back then and displays some footage from the archive.

American actress Sharon Stone talks about her memories of Rock Hudson and her work with amfAR. She reflects on AIDS and stigma, how to reach out to young people, and the importance of communication in order to change the sexual behaviors of young people.

M.D. Mervyn Silverman is one of the pioneers in the HIV/AIDS epidemic. Here he talks about the shifts of topics on the International AIDS Conferences between 1985 and 2008, about the so called San Francisco Model of AIDS care, and about the closing of the Bathhouses.