This film tells the US story of the AIDS epidemic starting in the early 1980's. Scientists and activists, both pioneers and youths of today, talk about research, prevention, treatment and care. They also discuss stigma, homophobia and poverty as closely related to HIV and AIDS.

Mr Subbarao is secretary of state for health in the Tamil Nadu Government in Chennai. In this interview he talks about the educational and medical work lead by the government. He talks particularly about empowering and educate women about HIV prevention.