This film is about the global AIDS situation. The film starts in Europe and the United States and ends up in Zimbabwe and Uganda. It tells about the global disparities of drug access, but also about the successful HIV and AIDS responses of Thailand, Cambodia and Uganda.

The primary focus of this documentary is on the history of how the AIDS epidemic started in San Francisco, Los Angeles and New York in 1981. Many different stories are told about people affected or surrounded by HIV and AIDS in the early years of the epidemic.

An agent from the AIDS NGO organization KHANA educates HIV/AIDS prevention by talking to some people and handing out information sheets on the street of Phnom Penh.

Quarraisha Abdool Karim is an epidemiologist in Durban. She talks about the start of the South African AIDS epidemic and the South African AIDS response, health policies and campaigns. She explains why women are more susceptible to HIV than men are.

Students are interviewed on the street in Washington DC, about HIV/AIDS and prevention.

Fernando Aiuti is an Italian Immunologist who has been working on HIV/AIDS since the early 80's. In this interview he talks about the Italian AIDS situation, sexuality education and the scientific and clinical work in the field.

Interview with Agneta Dreber from Folkhälsomyndigheten (National Institute of Public Health) in Sweden. She talks about the Swedish HIV/AIDS situation, about sexuality education in schools and HIV/AIDS education in workplaces.

This production from 1990 debates the worldwide HIV/AIDS situation for women and children. The stigmatization of female sexuality is considered the primary reason of women's particularly exposed situation when it comes to sexually transmitted diseases.

This production was made as the opening film for the IV International AIDS Conference in Stockholm in June 1988. It gives a broad representation of the global AIDS situation in the late 1980's, and has a particular focus on social structures, poverty and stigma.

A Philippine teacher talks about how Western, liberal values on sex is a threat to the youth. He also talks about tourism as an aspect of HIV transmission, and fears that the Philippine government suppresses information about AIDS to protect the tourist industry.

Julie and Ken from the Australian Prostitutes Collective talk about their program for HIV/AIDS prevention among female and male sex workers, among which one third are also IV drug users. APC offers social support, needle exchange and sex education.

Dr Robert Gallo is interviewed in the laboratory about the HIV virus and his ongoing work. He also talks with his team and discusses the question of international collaboration with Lars Olof Kallings. He answers questions about HIV and AIDS, drugs and promiscuity.