The Journalist David Perlman from San Francisco Chronicle was the first American journalist to report on AIDS in June 1981. He tells the story of his first article on AIDS, and how reporting on the epidemic affected him.

XIX International AIDS Conference. The co-chair of this conference, Diane Havlir, has been working with HIV/AIDS since the early 80's at San Francisco General Hospital. Here she talks about the time of the outbreak and about the tools needed to end HIV and AIDS.

XIX International AIDS Conference in Washington D.C. The speakers are the HIV/AIDS activists Phil Wilson and Cornelius Baker, Dr Sheldon Fields and Gregorio Millet from CDC who is also the Senior Advisor in the US Office of National AIDS Policy.

First part of the interview with the American AIDS activist and founder of Project Inform, Martin Delaney, in 2006. He talks about the HIV/AIDS policy of the current and previous American Presidents, and reflects on his experiences of the start of AIDS in the 80's.

The primary focus of this documentary is on the history of how the AIDS epidemic started in San Francisco, Los Angeles and New York in 1981. Many different stories are told about people affected or surrounded by HIV and AIDS in the early years of the epidemic.

Dr Selma Dritz tells the story of how the AIDS epidemic started in Los Angeles and San Francisco in the early 80's and how AIDS was connected to the gay liberation movement. She also talks about the government and community responses at that time.