The Swedish professor Emeritus in Infectious Diseases at Karolinska Institutet is interviewed about his memories and work as infectious disease physician in the 1980’s.

Two interviews with Dr Mervyn Silverman, from 1988 and 2008. He explains the San Francisco model, how it began and what others can learn from it.

Follow-up interview with Oum Sopheap who is the director of KHANA. He watches a clip from 1998 and talks about the situation back then and what has happened since 1998 in Cambodia.

XVII International AIDS Conference in Mexico City. Interview with three pioneers in the HIV/AIDS response - Dr Mervyn Silverman, Dr Paul Volberding, and Dr Lars Olof Kallings. They talk about the history of the AIDS movement.

Interview with Daniel Tarantola, Professor of Health and Human Rights at University of New South Wales in Sydney. He tells about his work in expanding health care services in several African countries, starting in the early 1970's and the time when he entered the HIV field.

Dr Selma Dritz tells the story of how the AIDS epidemic started in Los Angeles and San Francisco in the early 80's and how AIDS was connected to the gay liberation movement. She also talks about the government and community responses at that time.